Buy MK-677 Online — Ibutamoren, Research-Grade
The most studied orally active growth hormone secretagogue available. Independently verified to ≥99% purity via HPLC and Mass Spectrometry. Third-party COA on every batch. 50ml liquid and capsules in stock. Free US shipping over $100.
Third-Party COA
USA Lab Tested
50ml — 70% More Volume
Free Shipping $100+
4.9 / 5 — 847 verified research reviews
Research Compound Overview
What Is MK-677? Why Researchers Buy It Online
MK-677 (Ibutamoren, MK-0677) is a potent, orally active, non-peptide growth hormone secretagogue — a ghrelin receptor agonist (GHSR-1a) that stimulates the pituitary gland to release growth hormone and IGF-1 in animal research models. Unlike injectable GH secretagogue peptides like CJC-1295 or Ipamorelin, MK-677 is fully orally bioavailable — no reconstitution, no injection required for research protocols.
When you buy MK-677 online from Chemyo, you receive a compound independently verified to ≥99% purity via HPLC and Mass Spectrometry. Every batch receives a publicly published Certificate of Analysis, searchable by lot number directly on the product page.
Most vendors sell MK-677 in 30ml bottles at 10mg/ml — that’s only 300mg total. Chemyo’s 50ml bottles at 25mg/ml deliver 1,250mg total — over 4x more compound per bottle. Every batch is independently concentration-tested (not just purity-tested) to ensure what’s on the label matches what’s inside. That’s the Chemyo standard.
MK-677 Product Specifications
| Compound Name | MK-677 (Ibutamoren, MK-0677) |
| Class | GH Secretagogue / Ghrelin Receptor Agonist |
| Molecular Formula | C₂₇H₃₆N₄O₅S |
| Molecular Weight | 528.66 g/mol |
| CAS Number | 159634-47-6 |
| Purity (Chemyo) | ≥99% HPLC + Mass Spec verified |
| Concentration Testing | Yes — independently verified |
| Bottle Size | 50ml — 70% more than standard 30ml |
| Half-Life (animal) | ~24 hours (oral) |
| Available Forms | Liquid Solution (25mg/ml) · Capsules |
| Intended Use | Research purposes only — not for human use |
Mechanism of Action
How MK-677 Works — The GH Secretagogue Pathway
MK-677’s mechanism is distinct from every other growth hormone research compound. Understanding it is critical for accurate protocol design.
Available Formats
Buy MK-677 Online in Your Preferred Research Form
Chemyo offers MK-677 in multiple formats — all ≥99% purity, all independently concentration-tested. Every batch has a public COA.
25mg/ml in a 50ml induction-sealed bottle. 1,250mg total — over 4x more than the competitor’s standard 30ml at 10mg/ml. Ready to use, no reconstitution. Available in 50ml only.
10mg capsules, 60 per bottle. Pre-measured, convenient oral dosing. Ideal for long-duration protocols requiring precise daily administration with no measuring equipment.
Vendor Comparison
Chemyo vs Other MK-677 Vendors — Why Chemyo Wins
When you buy MK-677 online, the vendor matters more than the price. Here’s how Chemyo compares on the standards that actually protect your research.
| Standard | Chemyo | SwissChems | Generic Vendor |
|---|---|---|---|
| Purity testing (HPLC) | ✓ ≥99% | ✓ Yes | ✗ Unverified |
| Concentration testing | ✓ Independent lab | ✗ Not published | ✗ No |
| Identity testing (Mass Spec) | ✓ Every batch | ✗ Not confirmed | ✗ No |
| Batch-specific public COA | ✓ Every batch, searchable | Occasionally published | ✗ No |
| Bottle volume | 50ml (industry-leading) | 60 caps / 30ml | 30ml |
| MK-677 concentration | 25mg/ml = 1,250mg total | 10mg/cap = 600mg total | 10mg/ml = 300mg total |
| Induction sealed | ✓ Tamper-proof | ✗ Standard cap | ✗ No |
| US free shipping | ✓ Orders $100+ | Orders $75+ | Varies |
| Same-day dispatch | ✓ Before 2PM EST | 1–2 day processing | Varies |
Comparison based on publicly available vendor information as of April 2026. All MK-677 sold by Chemyo is for research purposes only.
Why Chemyo
Why Researchers Buy MK-677 Online From Chemyo
Most vendors test for purity only. Chemyo independently tests for all three — identity (Mass Spec), purity (HPLC), and concentration — on every single batch. Concentration testing is what confirms the label is accurate.
The industry standard is 30ml. Chemyo’s 50ml induction-sealed bottles deliver significantly more compound per purchase. At 25mg/ml, each bottle contains 1,250mg total — more than twice the competitor’s 600mg capsule bottle.
Every Chemyo MK-677 batch COA is published publicly and searchable by lot number on the product page. Verify your specific vial before your protocol starts. No other step matters more for research integrity.
Preclinical Research Overview
MK-677 Research: What the Data Shows
MK-677 has one of the most extensive preclinical and early clinical research profiles of any GH secretagogue. All data below reflects animal model and Phase I/II clinical findings. MK-677 is not FDA-approved for human use.
Primary Research Areas
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GH & IGF-1 Elevation: MK-677 consistently and sustainably increases both GH and IGF-1 in animal and early human studies. Unlike pulsatile peptide secretagogues, elevation is sustained — making it uniquely suited for long-duration research protocols.
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Lean Body Mass (Phase II Clinical): Published Phase II trials in healthy elderly subjects demonstrate statistically significant lean mass increases at oral doses — the most clinically advanced GH secretagogue endpoint in the literature.
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Bone Density Research: Phase II data shows MK-677 increases bone mineral density via sustained IGF-1 elevation. Studied in osteoporosis models and elderly populations with established efficacy signals.
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Sleep Quality Research: Animal and early human studies report MK-677 significantly increases REM sleep duration — an emerging area of circadian rhythm and recovery research.
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Muscle Wasting / Cachexia: Phase II trials in cancer cachexia and hip fracture patients show MK-677 preserves and increases lean mass — one of the most clinically significant GH secretagogue research applications.
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Cognitive & Neuroprotective Research: Emerging preclinical data examines MK-677’s role in cognitive function via IGF-1 pathway modulation — GH receptors expressed throughout brain tissue create a unique research avenue.
MK-677 Legal Status When You Buy Online in 2026
MK-677 is legal to purchase online in the United States as a research compound. It is not a controlled substance, not DEA-scheduled, and does not require a prescription when purchased strictly for laboratory research. Chemyo sells MK-677 in full regulatory compliance — labeled for research use only, not for human or animal consumption.
Research Reference
MK-677 Dosage Reference — Preclinical & Clinical Data Only
Summarized from published preclinical and Phase I/II clinical research. For reference only. Not a recommendation for human use.
| Research Protocol | Reported Dose | Route | Duration (Studies) |
|---|---|---|---|
| GH / IGF-1 Elevation (rodent) | 3–10 mg/kg/day | Oral gavage | 7–28 days |
| Lean Body Mass (Phase II) | 10–25 mg/day | Oral | 8–24 weeks |
| Bone Density (Phase II) | 10–25 mg/day | Oral | 12–24 months |
| Sleep Quality Research | 5–25 mg (early studies) | Oral | Acute – 2 weeks |
| Cachexia / Muscle Wasting | 25 mg/day (Phase II) | Oral | 12–24 weeks |
Data from peer-reviewed preclinical and Phase I/II literature. MK-677 is not FDA-approved. Human use is not endorsed.
Frequently Asked Questions
Buy MK-677 Online — Buyer FAQs
Related Growth Hormone & Recovery Research Compounds
Researchers studying MK-677 Solution 25mg/ml – 50ml often also explore
MK-2866 (Ostarine),
LGD-4033, and
RAD140 for broader anabolic and recovery research models.
For metabolic and endurance-related studies, MK-677 is frequently evaluated alongside
Cardarine (GW501516) in performance and body composition research protocols.
Liquid research workflows require precise dosing tools such as
1ml Dropper Bottles to ensure accurate measurement and reproducible laboratory results.
Reviews
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